SIZE-BASED SEPARATION METHOD FOR HIGHLY CONCENTRATING EXTRACELLULAR VESICLE FROM FLUID SAMPLE

摘要

The present invention relates to a method for concentrating extracellular vesicles from a fluid sample and, more particularly, to a method for concentrating extracellular vesicles within a short time at a high yield by using a 20-100 nm filter and controlling the composition of a fluid sample and the use of an eluting buffer. The use of the extracellular vesicle concentrating method of the present invention can simplify a concentration process, reduce a concentration time, and concentrate extracellular vesicles at high yield. The method reduces time and cost and increases a concentration yield, compared to conventional concentration methods and is proposed as an economically advantageous concentration method suitable for extracellular vesicles.