COMPOSITIONS COMPRISING HERPES SIMPLEX VIRUS-1 FOR USE IN METHODS OF TREATING AND PREVENTING CANCER

摘要

The present invention provides compositions for treating or preventing cancer and methods of using and making the compositions. The compositions comprise herpes simplex viruses comprising recombinant herpes simplex virus genomes. Further provided are recombinant herpes simplex virus genomes, viruses comprising the recombinant herpes simplex virus genomes, and cancer vaccines and other compositions comprising the viruses.