首页> 外国专利> ISOLITHOCHOLIC ACID OR ISOALLOLITHOCHOLIC ACID AND DEUTERATED DERIVATIVES THEREOF FOR PREVENTING AND TREATING CLOSTRIDIUM DIFFICILE-ASSOCIATED DISEASES

ISOLITHOCHOLIC ACID OR ISOALLOLITHOCHOLIC ACID AND DEUTERATED DERIVATIVES THEREOF FOR PREVENTING AND TREATING CLOSTRIDIUM DIFFICILE-ASSOCIATED DISEASES

机译：异硫氰酸或异硫代酸及其衍生物用于预防和治疗与艰难梭菌相关的疾病

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摘要

The present invention relates to isolithocholic acid (3ß-hydroxy-5ß-cholan-24-oic acid, iso-LCA) and isoallolithocholic acid (3ß-hydroxy-5α-cholan-24-oic acid) and their deuterated analogs for preventing or treating Clostridium difficile-associated disease in a mammalian subject.

机译：本发明涉及用于预防或治疗的异石胆酸（3β-羟基-5β-胆碱-24-oic酸，iso-LCA）和异卤代石胆酸（3β-羟基-5α-cholan-24-oic酸）及其氘代类似物。哺乳动物受试者与艰难梭菌相关的疾病。

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公开/公告号WO2020030737A1

专利类型
公开/公告日2020-02-13

原文格式PDF
申请/专利权人 PHENEX PHARMACEUTICALS AG;
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申请/专利号WO2019EP71315
发明设计人 GEGE CHRISTIAN;BIRKEL MANFRED;HOFFMANN THOMAS;
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申请日2019-08-08
分类号A61K31/575;C07J9;A61P31/04;
国家 WO
入库时间 2022-08-21 11:13:30

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