HIGH-SENSITIVE BIOSENSOR CHIP USING HIGH EXTINCTION COEFFICIENT MARKER AND DIELECTRIC SUBSTRATE, MEASUREMENT SYSTEM, AND MEASUREMENT METHOD

摘要

The present invention relates to a high-sensitive biosensor chip using a high extinction coefficient marker and a dielectric substrate, a measurement system, and a measurement method and, more specifically, to an ellipsometry-based high-sensitive biosensor technology or a measurement method using same, the technology amplifying an elliptically polarized signal by a marker having a high extinction coefficient and a dielectric substrate. The marker and the substrate used in the present invention measure a Brewster's angle shift or an elliptical polarization measurement angle with respect to an ultra-low concentration biological material (e.g. antibody or DNA).