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Heterobifunctional inhibitors of E-selectins and CXCR4 chemokine receptors
Heterobifunctional inhibitors of E-selectins and CXCR4 chemokine receptors
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机译:E-选择蛋白和CXCR4趋化因子受体的异双功能抑制剂
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摘要
Compounds, compositions, and methods for treatment and/or prevention of cancer and inflammatory diseases, and for releasing cells such as stem cells (e.g., bone marrow progenitor cells) into circulating blood and enhancing retention of the cells in the blood are disclosed. For example, heterobifunctional compounds that inhibit both E-selectins and CXCR4 chemokine receptors are described and pharmaceutical compositions comprising at least one of the same.
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