DIRECT DE-DIFFERENTIATION OF URINE CELL INTO NUERAL STEM CELL USING SYNTHETIC MESSENGER RNA

摘要

The present invention relates to a method for inducing a de-differentiation of neural stem cells from urine cells by introducing mRNAs of de-differentiation factors Oct4, Sox2, Klf4, and Glis1; and a composition for the prevention or treatment of neurological damage diseases comprising the neural stem cells induced by the method as an active ingredient.