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Article of manufacture comprising local anesthetic, buffer, and glycosaminoglycan in syringe with improved stability
Article of manufacture comprising local anesthetic, buffer, and glycosaminoglycan in syringe with improved stability
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机译:注射器中包含局部麻醉剂,缓冲剂和糖胺聚糖的制品,具有改善的稳定性
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摘要
An article of manufacture according to the present invention comprises a composition including a glycosaminoglycan, a local anesthetic, and a buffer packaged in a syringe or vial constructed from either glass or a plastic selected from the group consisting of cyclic olefin polymer, cyclic olefin copolymer, or high density non-nucleated polypropylene. The composition has unexpectedly improved stability on storage. The composition can be formulated for treatment of a urinary tract disease or condition, such as interstitial cystitis, also known as bladder pain syndrome or hypersensitive bladder syndrome.
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