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METHODS OF REDUCING- C-REACTIVE PROTEIN AND/OR TREATING CARDIOVASCULAR DISEASE

机译:减少C反应蛋白和/或治疗心血管疾病的方法

摘要

Provided herein are methods of preventing or treating cardiovascular disease (CVD), methods of supporting cardiovascular health, or supporting inflammatory health in a subject by reducing C-reactive protein (CRP). In exemplary aspects, the method comprises administering astaxanthin to the subject at a therapeutically effective amount. In some aspects, the subject also receives a standard of care for CVD or risk management thereof. The present disclosure also provides methods of reducing CRP levels in a subject comprising administering an amount of astaxanthin to the subject, as described herein, wherein the subject is at risk for or suffers from CVD. Additional related methods of altering levels of one or more of: TNF-α, IL-1β, IL-6, INF-γ, oxidized LDL, total cholesterol, LDL cholesterol, VLDL cholesterol, triglycerides, FOXO3 activation, and HDL cholesterol, comprising administering astaxanthin to the subject are further provided herein.
机译:本文提供了通过减少C反应蛋白(CRP)来预防或治疗对象的心血管疾病(CVD)的方法,支持对象的心血管健康或支持炎症性健康的方法。在示例性方面,该方法包括以治疗有效量向受试者施用虾青素。在一些方面,受试者还接受CVD或其风险管理的护理标准。本公开还提供了降低受试者中CRP水平的方法,包括向受试者施用一定量的虾青素,如本文所述,其中所述受试者有患CVD的风险或患有CVD。改变以下一种或多种水平的其他相关方法:TNF-α,IL-1β,IL-6,INF-γ,氧化的LDL,总胆固醇,LDL胆固醇,VLDL胆固醇,甘油三酸酯,FOXO3活化和HDL胆固醇,包括本文进一步提供了向对象施用虾青素。

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