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External preparation for treating trichophytosis unguium

机译:一种治疗毛癣菌的外用制剂

摘要

Provided is an external medicine for treating trichophytosis unguium, said external medicine being a non-coating type external medicine for treating trichophytosis unguium containing a medium-chain fatty acid triglyceride as a non-volatile component, which shows a high nail permeability, has excellent drug efficacy and formulation properties and, therefore, is clinically applicable. More particularly, provided is an external medicine for treating trichophytosis unguium which comprises a substance having antifungal activity such as efinaconazole, a volatile component, an additive such as a medium-chain fatty acid triglyceride and a permeation promoter such as ethyl lactate. This preparation shows a remarkably improved nail permeability and has excellent characteristics as a medicine from the viewpoint of drug efficacy and formulation properties.
机译:提供了一种治疗毛癣菌的外用药,所述外用药是非包衣型的治疗毛癣菌的外用药,其具有中链脂肪酸甘油三酸酯作为非挥发性成分,显示出高的指甲通透性,具有优异的药物。功效和制剂特性,因此可在临床上应用。更特别地,提供了一种用于治疗毛癣菌的外用药物,其包含具有抗真菌活性的物质例如艾芬那康唑,挥发性成分,添加剂例如中链脂肪酸甘油三酸酯和渗透促进剂例如乳酸乙酯。从药物功效和制剂性质的观点来看,该制剂显示出显着改善的指甲渗透性并且具有优异的药物特性。

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