Botulinum toxin formulations and methods of use thereof in plantar fasciitis with extended duration of effect

摘要

This invention relates to injectable and transdermal compositions comprising botulinum toxin and their methods of use in administering botulinum toxin to treat or manage plantar fasciitis, a disorder related thereto, or a symptom thereof. The injectable and transdermal compositions and methods in which these compositions are used provide advantageous treatments which result in fast onset, higher responder rates, and/or long duration of effect, for example, a duration of effect for over six months and/or a reduction in plantar fasciitis pain by at least 50% maintained through week 8 following treatment. The topical compositions and methods provide desirable, less painful, treatment alternatives.