Label-free optical detection in capture zones immobilized on strips for lateral flow assays

摘要

A test strip comprising a porous matrix, the test strip comprising a sample application zone for applying a liquid sample comprising an analyte; a reporter release zone, comprising a sensing material, the sensing material being adapted to selectively interact with the analyte by releasing an optical reporter, the reporter release zone being arranged downstream of the sample application zone; and a detection zone, comprising a capture material, the capture material being adapted to selectively bind the optical reporter and being arranged downstream of the reporter release zone..