Antibody construct-drug conjugate for the treatment of hepatitis

摘要

Various compositions are disclosed for the treatment of viral infections. The compositions comprise antibody constructs directed to the liver, attached to myeloid cell agonists, specifically TLR7 and TLR8 agonists, via a linker. Additionally provided are the methods of preparation and use of the conjugates. This includes methods for treating viral infections, such as viral liver diseases.