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ANTI-HUMAN CARDIOMYOPATHY ANTIBODY CONTAINING CARDIAC TROPONIN AND APPLICATION THEREOF

机译:含心肌肌钙蛋白的抗人心肌肌病抗体及其应用

摘要

Disclosed by the present invention are an isolated binding protein containing a cardiac troponin I (cTnI) antigen binding domain, a preparation therefor, an application thereof and the like. The antigen binding domain comprises at least one complementary determining region selected from an amino acid sequence defined in the present invention or has at least 80% sequence identity with the complementary determining region of the amino acid sequence and has an affinity for cTnI of KD≤9.96×10-8mol/L. The present binding protein may be used in the field of cTnI protein detection.
机译:本发明公开了一种分离的结合蛋白,其含有心肌肌钙蛋白I(cTnI)抗原结合结构域,其制备方法,其应用等。抗原结合结构域包含至少一个选自本发明定义的氨基酸序列的互补决定区,或者与氨基酸序列的互补决定区具有至少80%的序列同一性,并且对cTnI具有K D ≤9.96×10 -8 mol / L。本结合蛋白可用于cTnI蛋白检测领域。

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