BIOMARKER COMPOSITION FOR DIAGNOSING MASSIVE PERIVILLOUS FIBRIN DEPOSITION ASSOCIATED WITH MISCARRIAGE, AND USE THEREOF

摘要

The present invention pertains to a biomarker composition for diagnosing massive perivillous fibrin deposition (MPFD) associated with miscarriage and a use thereof. A protein contained as an active ingredient in the biomarker composition according to the present invention for diagnosing massive perivillous fibrin deposition associated with miscarriage is specifically found only in maternal blood diagnosed with fibrin-type MPFD (f-MPFD), and can thus be useful for diagnosis with f-MPFD and prevent in advance habitual miscarriage caused by f-MPFD. Moreover, the diagnosis of MPFD provides opportunities for further testing and the early detection of MPFD-associated blood hypercoagulation disorders in mothers diagnosed with MPFD, and can prevent and treat serious complications that arise from blood hypercoagulation disorders.