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Hydrophobic Auristatin F compounds and conjugates thereof
Hydrophobic Auristatin F compounds and conjugates thereof
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机译:疏水性Auristatin F化合物及其缀合物
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摘要
Ligand Drug Conjugates of hydrophobically-modified auristatin F compounds that exhibit cytotoxic activities towards targeted cells, including abnormal cells such as cancer cells, that are MDR+ while also exhibiting bystander activities towards nearby cells having lower expression of the moeity targeted by the Conjugate.
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