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METHOD FOR PRODUCING DRIMANYL ACETATE COMPOUNDS

机译：醋酸丁三酸酯化合物的制备方法

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摘要

The present invention provides novel methods for the acetyl transferase-catalyzed production of drimanyl- acetate compounds by the acetylation of the respective drimanyl alcohol sources performed in vitro or in vivo. The present invention also relates to the identification of enzymes having corresponding acetyl transferase activity from different microbial and plant sources. The present invention also relates to the provision of enzyme mutants derived from said newly identified enzymes. A further aspect of the present invention relates to the provision of corresponding coding sequences of such enzymes and mutants, recombinant vectors, and recombinant host cells suitable for the production of such acetyl transferases and mutants and for performing the novel production methods of drimanyl acetate compounds. Another aspect of the invention relates to the use of such drimanyl acetates, as obtained according to the present invention, as intermediates for the production of odorant, flavor or fragrance or insect/pest control ingredients.

机译：本发明提供了新的方法，该方法通过在体外或体内进行的乙酰基转移酶催化的乙酰基乙酸酯化合物的生产，该方法是通过相应的德里基醇源的乙酰化进行的。本发明还涉及从不同的微生物和植物来源鉴定具有相应的乙酰转移酶活性的酶。本发明还涉及衍生自所述新鉴定的酶的酶突变体的提供。本发明的另一个方面涉及提供适合于产生这种乙酰基转移酶和突变体并用于执行新的乙酸十二烷基酯化合物的这种酶和突变体，重组载体和重组宿主细胞的相应编码序列。本发明的另一方面涉及根据本发明获得的这种乙酸十二烷基乙酸酯作为中间体的用途，所述中间体用于生产增香剂，调味剂或香料或昆虫/害虫防治成分。 展开▼

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公开/公告号WO2020078871A1

专利类型

公开/公告日2020-04-23

原文格式PDF

申请/专利权人 FIRMENICH SA;
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申请/专利号WO2019EP77716

发明设计人 SOLIS ESCALANTE DANIEL;GÖRNER CHRISTIAN;DAVIET LAURENT;WANG QI;
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申请日2019-10-14

分类号C12P7/62;C12N9/10;

国家 WO

入库时间 2022-08-21 11:11:50

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