CARBOXYLIC ACID-TYPE LIPID, AND LIPID PARTICLE AND LIPID MEMBRANE CONTAINING CARBOXYLIC ACID-TYPE LIPID

摘要

The purpose of the present invention is to provide: a carboxylic acid-type lipid which can promote adhesion and coagulation of platelets without carrying a protein or peptide (e.g., GPIb or H12) which is involved in adhesion or coagulation of platelets; lipid particles containing the carboxylic acid-type lipid; a lipid membrane containing the carboxylic acid-type lipid; and a platelet coagulation promoting agent, a platelet adhesion promoting agent, a hemostatic agent, and a platelet alternative which contain the carboxylic acid-type lipid, the lipid particles, or the lipid membrane. To achieve the purpose, the present invention provides: a carboxylic acid-type lipid selected from carboxylic acid-type lipids represented by formulae (I) to (VI); lipid particles containing the carboxylic acid-type lipid; a lipid membrane containing the carboxylic acid-type lipid; and a platelet coagulation promoting agent, a platelet adhesion promoting agent, a hemostatic agent, and a platelet alternative which contain the carboxylic acid-type lipid, the lipid particles, or the lipid membrane.