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Reprogramming of non-neuronal cells into neurons and methods and compositions to treat neurodegenerative diseases and disorders
Reprogramming of non-neuronal cells into neurons and methods and compositions to treat neurodegenerative diseases and disorders
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机译:将非神经元细胞重编程为神经元以及治疗神经退行性疾病和病症的方法和组合物
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摘要
Provided herein is a method of reprogramming a non-neuronal cell to a neuron. Aspects of the present disclosure relate to using cell reprogramming agent suppresses the expression or activity of PTB to convert a non-neuronal cell into a neuron. Also provided herein is a method of treating neurodegenerative disease by reprogramming non-neuronal cells in vivo to functional neurons.
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