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NOVEL PEPTIDE BINDING SPECIFICALLY TO HUMAN SERUM ALBUMIN, AND USES THEREOF

机译:新型肽与人血清白蛋白的特异性结合及其用途

摘要

The present invention relates to a novel peptide binding specifically to human serum albumin, more specifically to a peptide binding specifically to human serum albumin, polynucleotides coding for the polypeptide, an expression vector comprising the polynucleotides, a transgenic organism into which the expression vector has been introduced, and a method for producing the polypeptide by means of the transgenic organism. The novel peptide according to the present invention binds specifically to human serum albumin and increases the in-blood circulation time and half-life of low molecular weight protein or peptide to increase the bioavailability thereof, and thus can be broadly applied as a new system that increases the effectiveness of drug treatment.
机译:本发明涉及特异性结合人血清白蛋白的新型肽,更具体地涉及特异性结合人血清白蛋白的肽,编码该多肽的多核苷酸,包含该多核苷酸的表达载体,该表达载体已被转入其中的转基因生物。介绍了一种通过转基因生物生产多肽的方法。根据本发明的新型肽与人血清白蛋白特异性结合,并增加了低分子量蛋白质或肽的血液循环时间和半衰期,从而提高了其生物利用度,因此可以广泛地用作新系统增加药物治疗的有效性。

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