Pyrimidine compositions, ultra-pure compositions and salts thereof, methods of making the same, and methods of using the same for treating histamine H4 receptor (H4) mediated diseases and conditions

摘要

#$%^&*AU2020200840A120200227.pdf#####l:[nterwoenNRPortbIDCCAAR 19835068 docx-2 62020 ABSTRACT The present application relates to ultra-pure compositions containing N4(cyclopropylmethyl)-6-[(3R)-3-(methylamino)pyrrolidin-1-yl]pyrimidine-2,4-diamine tartrate dihydrate, methods of making the same, formulations containing the same, methods of using the same to treat H4-mediated diseases and conditions, and alternative salt forms thereof 111