SYSTEMS AND METHODS FOR RNA ANALYSIS IN FUNCTIONAL CONFIRMATION OF CANCER MUTATIONS

摘要

#$%^&*AU2020201237A120200312.pdf#####Abstract Contemplated systems and methods integrate genomic/exomic data with transcriptomic data by correlating a cancer associated mutation in the genome/exome with the transcription level of the affected gene carrying the mutation, particularly where the mutation is a 3-terminal nonsense mutation.WO 2015/148689 PCT/US2015/022521 1/14 100 Memory Processor (RAM, Flash, SAN, RAID, Etc.) 140 Analysis Engine 150 Genomic Data Set --120 Data Set Association Transcriptomic Data Set (Genomic/Transcriptomic Data Set) 0152 Software Instructions 112 Mutation Identification 154 Position Identification 156 Expression Level Identification 158 Data Set Generator 151 Omics Database Sequence Database or Sequencing Device 160 170 * Patient specific omics information * Genomics/Exomics * Transcriptomics * Proteomics • Etc. Figure 1