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PHOSPHOLIPID-FREE SMALL UNILAMELLAR VESICLES (PFSUVS) FOR DRUG DELIVERY

机译:不含磷脂的小单片囊泡(PFSUVS)

摘要

Provided herein are phospholipid-free small unilamellar vesicle (PFSUV) compositions, including a steroid and a nonionic surfactant wherein the molar ratio of steroid:nonionic surfactant is between 3:1 to 5:1. Furthermore, the compositions described herein were found to useful for drug loading, drug delivery where preferential targeting of drugs to the liver is of interest.
机译:本文提供了不含磷脂的小单层小囊泡(PFSUV)组合物,包括类固醇和非离子表面活性剂,其中类固醇:非离子表面活性剂的摩尔比为3:1至5:1。此外,发现本文所述的组合物可用于药物装载,药物递送,其中关注将药物优先靶向肝。

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