FUNCTION OPTIMIZATION ALGORITHM AND MULTI-TYPE ELECTROTHERAPY COMBINATION TREATMENT

摘要

#$%^&*AU2020204612A120200730.pdf#####Abstract A multi-type electrotherapy system for non-invasive treatment of both surface and deep body bacterial and viral infections and wound healing, the system comprising: a machine learning function optimization task algorithm, and a stimulation device electronically designed to include the ability to generate carrier base waveforms with amplitude modulation of these waveforms by secondary frequencies. The ranges of such frequencies are preferably base frequencies in the range of 1-20,000 Hz and modulating frequencies in the range of 1-200 Hz. The waveforms are preferably generated by either direct digital synthesis (DDS) or digital to analogue (DAC) converter electronics.MULTI TYPE ES WOUNDHEALINGFLOWCHART1/12 MLO On power down, save last timeZRmeanlog, current ASS, ML1-1 ML1Eand ASS Score Table. ML1-2 [YES] Continue R e log,91GUI load ASS and ASS Score Table. AS=RE[NO] Clear R ma log and Get user mnput load DefaultASS SAME WOUND ? [YES] [NO] Parameters-VariablesI TimeCelMod = 5 seconds TimeLIDC = 10 seconds ML -3Time-rest=2seconds TimeEF = 10 seconds Identify Wound Procedure (IWP) cymake = 2 seconds ITime cyclic rest= 1second •Check second-stage stability and Timecyclicutil=2seconds elctodcotatLIDC bacteria= 2.5 microAmps continuity of electrodeIcontactLIDC virus = 7.5 microAmps LIDCfungus = 1.5 microAmps •Determine configuration of LIDC yeast = 9.9 microAmps electrodes to wound •Output a calibrated mean through-wound resistance value (R_wound) ML2ML1-5 ML1-4 ML1-12 Check ASS flag: Menu [TRUE] Load ASS. STIM CODE Rest period [FALSE] Load switch set Show current/last under test. ASS, ASS flag • No current in any direction for time Ystatus,andscroll • Allow pH under electrode to stabilize ML1-6 •Minimize cell hyperpolarization LowIntensityDirectCurrentStimulation(LIDC) ML1-9-1 "*Output LIDC at algorithm generated value Jump if GB or •*Reverse polarity for X time to clean lB1selected in electro-chemical debris from electrodes switch set under test or in current ASS cAMPI ML1-8 cAMP cGMP CM1 |cAMP_HZ1-GB--B GB ' B --------. CM1-5 cGMP_HZ1 - -CM1-2cAMP Rest CM1-6cGMP Rest1 CM1-3cAMPHZ2 CM1-7cGMPHZ2 CM1-4cAMPRest2 ML1-10-- ML1-9 VI1L1-11 Electric Field Stimulation (EF) Cell Modification Stimulation (CELLMOD) • Scale electric field (EF) to stage of Scale electric field (EF) for cell wound healing based on R_wound phenotype modification •oCalibrate EF to electrode •Calibrate EF to electrode configuration and positioning configuration and positioning •dApply matching polarity EF based on •Output EF electrode configuration FIGURE 6 •*Output EF