首页> 外国专利> DNA IMMUNOADSORBENT USING NANO-SELENIUM AS ADSORBENT CARRIER, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF

DNA IMMUNOADSORBENT USING NANO-SELENIUM AS ADSORBENT CARRIER, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF

机译:纳米硒作为吸附载体的DNA免疫吸附剂,制备方法及其应用

摘要

A DNA immunoadsorbent using nano-selenium as an adsorbent carrier, a preparation method therefor, and an application thereof, wherein the DNA solid load of the immunoadsorbent is large, adsorption performance is good, and safety performance is better. In the described DNA immunoadsorbent, DNA molecules and anti-dsDNA antibodies sufficiently touch, and the immunoadsorbent may be used for immunofluorescence and for qualitatively analyzing anti-dsDNA antibodies deposited in kidney tissue, and may specifically confirm the deposition and distribution of anti-dsDNA antibodies in kidney tissue, while operation is simple and the immunoadsorbent is suitable for preparing a reagent for detecting and analyzing lupus nephritis and systemic lupus erythematosus.
机译:一种以纳米硒为吸附载体的DNA免疫吸附剂,其制备方法及其应用,其中免疫吸附剂的DNA固载量大,吸附性能好,安全性能较好。在所描述的DNA免疫吸附剂中,DNA分子和抗dsDNA抗体充分接触,并且该免疫吸附剂可以用于免疫荧光和定性分析在肾脏组织中沉积的抗dsDNA抗体,并且可以特异性地确认抗dsDNA抗体的沉积和分布。在肾脏组织中,该方法操作简单且免疫吸附剂适合于制备用于检测和分析狼疮性肾炎和系统性红斑狼疮的试剂。

著录项

  • 公开/公告号WO2020093989A1

    专利类型

  • 公开/公告日2020-05-14

    原文格式PDF

  • 申请/专利权人 JINAN UNIVERSITY;

    申请/专利号WO2019CN115559

  • 发明设计人 CHEN TIANFENG;LIN ZHIMING;

    申请日2019-11-05

  • 分类号G01N33/533;B01J20/02;

  • 国家 WO

  • 入库时间 2022-08-21 11:11:15

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