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METHOD OF IMPROVING PREDICTION OF RESPONSE FOR CANCER PATIENTS TREATED WITH IMMUNOTHERAPY
METHOD OF IMPROVING PREDICTION OF RESPONSE FOR CANCER PATIENTS TREATED WITH IMMUNOTHERAPY
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机译:改善免疫疗法治疗癌症患者反应预测的方法
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摘要
A method of determining a therapeutic regimen in a patient with cancer comprising determining in a sample from the patient the tumor mutation burden (TMB) and loss of heterozygosity (LOH), wherein high TMB in combination with no LOH is indicative of a positive outcome when treated with a checkpoint inhibitor and high TMB with LOH is indicative of a poor outcome, is provided herein.
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