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SCYLLA PARAMAMOSAIN ANTIBACTERIAL PEPTIDE SCYREPROCIN AND APPLICATION THEREOF

机译:巴拉圭沙门氏菌抗菌肽Scyreprocin及其应用

摘要

Provided are Scylla paramamosain antibacterial peptide Scyreprocin and an application thereof, wherein the amino acid sequence thereof comprises a sequence as shown in SEQ ID NO 01, and the antibacterial peptide is expressed and purified by using genetic engineering technology. The antibacterial peptide has advantages of wide antibacterial spectrum, good antibacterial effect, and fast sterilization rate, shows great application significance, and has good application in preparation of antibacterial agents. The antibacterial peptide has no cytotoxicity to mouse hepatocytes AML 12, human normal liver cells L02 and the like, and can be safely used for medical treatment or can be used as a feed composition.
机译:本发明提供了Scyla paramamosain抗菌肽Scyreprocin及其应用,其中,其氨基酸序列包括SEQ ID NO 01所示的序列,并通过基因工程技术表达和纯化。本发明的抗菌肽具有抗菌谱广,抗菌效果好,杀菌速度快的优点,具有重要的应用意义,在抗菌剂的制备中具有良好的应用前景。该抗菌肽对小鼠肝细胞AML 12,人正常肝细胞L02等没有细胞毒性,可以安全地用于医疗或可以用作饲料组合物。

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