THERAPEUTIC TARGET AND MONOCLONAL ANTIBODIES AGAINST IT FOR THE DIAGNOSIS AND TREATMENT OF ALZHEIMER´S DISEASE

摘要

The invention provides a therapeutic target for the screening of drugs for the treatment of Alzheimer's disease (AD), as well as neutralizing monoclonal antibodies against said target and their use for the treatment of AD. The invention also refers to a kit comprising the antibodies and to an in vitro method for the diagnosis of AD in which preferably the antibodies or the kit comprising them are used.