首页> 外国专利> METHOD FOR DIAGNOSING OR FOR PROVIDING A PROGNOSIS OF A SUBJECT SUFFERING FROM OESOPHAGOGASTRIC CANCER, OR A PRE-DISPOSITION THERETO.

METHOD FOR DIAGNOSING OR FOR PROVIDING A PROGNOSIS OF A SUBJECT SUFFERING FROM OESOPHAGOGASTRIC CANCER, OR A PRE-DISPOSITION THERETO.

机译:诊断或提供食管胃癌患者预后的方法或对其进行预处置的方法。

摘要

The invention relates to a method for diagnosing or for providing a prognosis of a subject suffering from oesophagogastric cancer, or a pre-disposition thereto. The method comprises analysing, in an endoluminal sample obtained from a test subject, the level of at least one biomarker compound selected from the group consisting of: acetone, acetic acid, butyric acid, pentanoic acid and hexanoic acid. The method further comprises comparing this level with a reference for the level of the at least one biomarker compound in an individual who does not suffer from oesophagogasatric cancer. In particular, an increase in the concentration of the at least one biomarker compound, in the endoluminal sample from the test subject, compared to the reference, suggests that the subject is suffering from oesophagogastric cancer, or has a pre- disposition thereto, or provides a negative prognosis of the subject's condition.
机译:本发明涉及一种用于诊断或提供患有食管胃癌的受试者或其易患病的预后的方法。该方法包括在从测试对象获得的腔内样品中分析选自丙酮,乙酸,丁酸,戊酸和己酸的至少一种生物标记化合物的水平。所述方法进一步包括将该水平与在没有患有食管胃癌的个体中的至少一种生物标记化合物的水平的参考进行比较。特别地,与参考相比,来自测试对象的腔内样品中至少一种生物标记化合物的浓度增加表明该对象患有食管胃癌,或对此具有易感性,或提供受试者状况的阴性预后。

著录项

  • 公开/公告号WO2020165579A1

    专利类型

  • 公开/公告日2020-08-20

    原文格式PDF

  • 申请/专利权人 IMPERIAL COLLEGE INNOVATIONS LIMITED;

    申请/专利号WO2020GB50317

  • 发明设计人 HANNA GEORGE;BOSCHIEN PIERS;

    申请日2020-02-12

  • 分类号G01N33/574;G01N33/497;

  • 国家 WO

  • 入库时间 2022-08-21 11:09:49

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