A METHOD TO PREDICT A PATIENT'S RESPONSE TO AN ANTI-CANCER DRUG FROM AN EXPRESSION LEVEL OF A SET OF GENES

摘要

Provided are methods and kits for predicting a patient's response to an anti-cancer drug. The method comprises determining in a control biological sample an expression level of a set of genes to obtain a pre-treatment gene expression level, determining in a drug treated biological sample an expression level of the set of genes to obtain a post-treatment gene expression level, and comparing the post-treatment gene expression level to the pre-treatment gene expression level. If the post-treatment gene expression level is greater than the pre-treatment gene expression level, the patient is predicted to respond to the anti-cancer drug and if the post-treatment gene expression level is less than the pre-treatment gene expression level, the patient is predicted not to respond to the anti-cancer drug.