首页> 外国专利> ANTERIOR CHAMBER PERFUSATE FOR INTRAOCULAR SURGERY AND USE THEREOF

ANTERIOR CHAMBER PERFUSATE FOR INTRAOCULAR SURGERY AND USE THEREOF

机译:前腔灌注液用于眼内手术及其用途

摘要

Disclosed are an anterior chamber perfusate for intraocular surgery and a use thereof; under the effect of balanced intraocular pressure, also containing a certain amount of L-alanyl-L-glutamine. Extracapsular cataract extraction, intraocular lens implantation, vitrectomy, and other intraocular operations require a relatively long time for liquid perfusion; a commonly used ophthalmic perfusate is a balanced saline solution, which lacks nutrients and antioxidant effectiveness, and has an impact on corneal endothelial cells that cannot be ignored. The anterior chamber perfusate for intraocular surgery provided by the present invention is used for intraoperative perfusion, has a protective effect against intraoperative mechanical injury of corneal endothelial cells and ischemia and hypoxia and provides nutrients, and can preventively reverse corneal endothelial cell apoptosis and denudation, protecting the corneal endothelial barrier function, achieving better surgical results.
机译:公开了一种用于眼内手术的前房灌流液及其用途。在平衡眼压的作用下,还含有一定量的L-丙氨酰-L-谷氨酰胺。白内障囊外摘除术,人工晶状体植入术,玻璃体切除术和其他眼内手术需要相对较长的时间进行液体灌注。常用的眼用灌注液是平衡盐溶液,缺乏营养和抗氧化作用,并且对角膜内皮细胞有不可忽视的影响。本发明提供的眼内手术前房灌注液用于术中灌注,对术中角膜内皮细胞的机械损伤,局部缺血缺氧有保护作用,并提供营养,可以预防角膜内皮细胞的凋亡和剥脱,保护角膜内皮屏障功能,取得较好的手术效果。

著录项

  • 公开/公告号WO2020173484A1

    专利类型

  • 公开/公告日2020-09-03

    原文格式PDF

  • 申请/专利权人 XIAMEN UNIVERSITY;

    申请/专利号WO2020CN76984

  • 发明设计人 LI CHENG;JIN MENGYI;HONG YING;LIU ZUGUO;

    申请日2020-02-27

  • 分类号A61K9/08;A61K47/02;A61K47/12;A61K31/198;A61P41;

  • 国家 WO

  • 入库时间 2022-08-21 11:09:40

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