首页>
外国专利>
CANCER THERAPY USING 3,5-DISUBSTITUTED BENZENE ALKYNYL COMPOUND AND IMMUNE CHECKPOINT INHIBITOR
CANCER THERAPY USING 3,5-DISUBSTITUTED BENZENE ALKYNYL COMPOUND AND IMMUNE CHECKPOINT INHIBITOR
展开▼
机译:使用3,5-二取代的苯炔基化合物和免疫检查点抑制剂对癌症进行治疗
展开▼
页面导航
摘要
著录项
相似文献
摘要
The present disclosure addresses the problem of providing a new combination therapy that exhibits a superior anti-tumor effect in cancer patients who have a resistance to immune checkpoint inhibitors, said combination therapy involving (S)-1-(3-(4-amino-3-((3,5-dimethoxyphenyl)ethynyl)-1H-pyrazolo[3,4-d]pyrimidine-1-yl(pyrrolidine-1-yl)prop-2-en-1-one or a salt thereof. The present disclosure provides an anti-tumor agent for concomitant administration with an immune checkpoint inhibitor (excluding pembrolizumab) to cancer patients who have a resistance to immune checkpoint inhibitors, said anti-tumor agent including a (S)-1-(3-(4-amino-3-((3,5-dimethoxyphenyl)ethynyl)-1H-pyrazolo[3,4-d]pyrimidine-1-yl(pyrrolidine-1-yl)prop-2-en-1-one or a salt thereof as an active component.
展开▼