首页> 外国专利> AMORPHOUS SOLID DISPERSION OF PYRAZOLE-AMIDE COMPOUND

AMORPHOUS SOLID DISPERSION OF PYRAZOLE-AMIDE COMPOUND

机译:吡唑酰胺化合物的非晶态固体分散体

摘要

The purpose of this invention is to provide a pharmaceutical preparation having improved pharmacokinetics which contains a compound of formula [I] or a pharmaceutically acceptable salt or hydrate thereof, and a method for producing the same. This invention relates to a solid dispersion and a method for producing the same, the solid dispersion containing: (1) an amorphous compound represented by formula [I] or a pharmaceutically acceptable salt or hydrate thereof; and (2) one to four types of pharmaceutically acceptable polymers selected from the group consisting of hydroxypropyl methylcellulose acetate succinate, methylcellulose, hypromellose, and polyvinyl alcohol.
机译:本发明的目的是提供包含式[I]化合物或其药学上可接受的盐或水合物的具有改善的药代动力学的药物制剂及其制备方法。本发明涉及一种固体分散体及其制备方法,该固体分散体包含:(1)式[I]代表的无定形化合物或其药学上可接受的盐或水合物; (2)选自羟丙基甲基纤维素乙酸琥珀酸酯,甲基纤维素,羟丙甲纤维素和聚乙烯醇中的1-4种可药用聚合物。

著录项

  • 公开/公告号WO2020179770A1

    专利类型

  • 公开/公告日2020-09-10

    原文格式PDF

  • 申请/专利权人 JAPAN TOBACCO INC.;

    申请/专利号WO2020JP08840

  • 申请日2020-03-03

  • 分类号A61K31/415;A61K9/10;A61K9/20;A61K9/28;A61K9/36;A61K47/02;A61K47/04;A61K47/32;A61K47/38;A61P3/06;A61P3/08;A61P3/10;A61P9/04;A61P9/10;A61P9/12;A61P11;A61P21;A61P25;A61P35;A61P43;

  • 国家 WO

  • 入库时间 2022-08-21 11:09:33

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