首页> 外国专利> AMORPHOUS FORM OF HETEROCYCLIC COMPOUND, SOLID DISPERSION AND PHARMACEUTICAL PREPARATION EACH COMPRISING THE SAME, AND PROCESS FOR PRODUCTION OF THE SAME

AMORPHOUS FORM OF HETEROCYCLIC COMPOUND, SOLID DISPERSION AND PHARMACEUTICAL PREPARATION EACH COMPRISING THE SAME, AND PROCESS FOR PRODUCTION OF THE SAME

机译:异质化合物的异构体形式,固体分散体和药物制备,均包含相同的化合物,并且其制备过程

摘要

[PROBLEMS] The object is to improve the absorbability of a heterocycliccompoundincluding s-triazine and a pyrimidine derivative in vitro. [MEANS FOR SOLVINGPROBLEMS]Disclosed is, for example, an amorphous form of a heterocyclic compound asrepresented by thegeneral formula (I) [wherein each of R's and others is as defined in thedescription] includings-triazine and a pyrimidine derivative, or a hydrate, a solvate or apharmaceutically acceptable saltof the heterocyclic compound. Also disclosed is a process for producing theamorphous form.Further disclosed are: a solid dispersion comprising the amorphous body; and amedicinalpreparation comprising the solid dispersion.(see formula I)
机译:[问题]目的是提高杂环的吸收性复合包括s-三嗪和嘧啶衍生物。 [解决方法问题]公开了例如无定形形式的杂环化合物,如以通式(I)[其中R和其他基团的定义如说明],包括s-三嗪和嘧啶衍生物,或水合物,溶剂化物或药学上可接受的盐杂环化合物。还公开了一种生产无定形形式。还公开了:包含无定形体的固体分散体;和和一个药用的包含固体分散体的制剂。(参见公式I)

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