首页> 外国专利> CONCEALMENT OF HYPOMINERALISED LESIONS

CONCEALMENT OF HYPOMINERALISED LESIONS

机译:隐匿性病变的隐匿

摘要

The present invention relates to compositions and uses for reducing the visibility of hypomineralised dental surfaces or subsurfaces, in particular in dental enamel. In one aspect, the invention involves a method of reducing visibility of a hypomineralised dental surface or subsurface, the method comprising (i) contacting the hypomineralised dental surface or subsurface with a liquid composition comprising at least 40% w/v of phosphopeptide (PP)-stabilized amorphous calcium phosphate (ACP) and/or amorphous calcium fluoride phosphate (ACFP) at a pH of less than or equal to pH 6; and (ii) subsequently to (i), raising the pH of the liquid composition applied to the hypomineralised dental surface or subsurface to equal to, or greater than, about 9, thereby forming a gel in and/or on the hypomineralised dental surface or subsurface, thereby reducing visibility of a hypomineralised dental surface or subsurface.
机译:本发明涉及用于降低矿化程度低的牙齿表面或亚表面,特别是在牙釉质中的可见性的组合物和用途。在一个方面,本发明涉及一种降低矿化程度低的牙齿表面或亚表面的可见性的方法,该方法包括(i)使该矿化程度低的牙齿表面或亚表面与包含至少40%w / v的磷酸肽(PP)的液体组合物接触。 -在小于或等于pH 6的pH下稳定的无定形磷酸钙(ACP)和/或无定形氟化钙(ACFP); (ii)在(i)之后,将施用于矿化不足的牙齿表面或亚表面的液体组合物的pH值提高到等于或大于约9,从而在矿化不足的牙齿表面内和/或上形成凝胶,或者地下,从而降低了矿化度低的牙齿表面或地下的可见性。

著录项

  • 公开/公告号WO2020181335A1

    专利类型

  • 公开/公告日2020-09-17

    原文格式PDF

  • 申请/专利权人 THE UNIVERSITY OF MELBOURNE;

    申请/专利号WO2020AU50239

  • 发明设计人 REYNOLDS ERIC CHARLES;

    申请日2020-03-13

  • 分类号A61K6/76;A61K6/838;A61K6/20;A61K8/21;A61Q11;A61K8/24;A61K33/06;A61K33/16;A61K33/42;A61K9/08;

  • 国家 WO

  • 入库时间 2022-08-21 11:09:33

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