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CANNABINOID COMBINATIONS FOR TREATING CHRONIC PAIN IN DIALYSIS PATIENTS

机译:大麻素组合物治疗糖尿病患者的慢性疼痛

摘要

The present invention is directed to a cannabinoid combination comprising, as the only cannabinoids, cannabidiol (CBD) and A9-tetrahydrocannabinol (THC), or enantiomers, diastereomers, or racemates thereof, for use in the treatment of chronic pain and associated symptoms in a subject suffering from end-stage renal disease (ESRD) and treated with dialysis, or for improving the efficacy and/or reducing adverse effects of at least one analgesic used for treating pain in a subject suffering from ESRD and treated with dialysis, wherein the CBD:THC weight ratio in the cannabinoid combination is about of 4:1 to about 10:1, preferably about 6:1.
机译:本发明涉及一种大麻素组合,其包含大麻脂(CBD)和A9-四氢大麻酚(THC),或其对映异构体,非对映异构体或外消旋体,作为唯一的大麻素,用于治疗慢性疼痛和相关症状。患有终末期肾病(ESRD)并接受透析治疗的受试者,或用于改善至少一种用于治疗ESRD并接受透析治疗的受试者的疼痛的止痛药的功效和/或减轻其不良影响的方法,其中,大麻素组合中的∶THC重量比为约4∶1至约10∶1,优选约6∶1。

著录项

  • 公开/公告号WO2020183456A1

    专利类型

  • 公开/公告日2020-09-17

    原文格式PDF

  • 申请/专利权人 BOL PHARMA LTD.;

    申请/专利号WO2020IL50271

  • 发明设计人 GEDO TAMIR;

    申请日2020-03-09

  • 分类号A61K31/352;A61K47;A61K36/185;A61K9;A61P13/12;A61P25/04;

  • 国家 WO

  • 入库时间 2022-08-21 11:09:27

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