IMMUNODOMINANT PROTEIN BASED METHOD FOR DIFFERENTIATING BRUCELLOSIS-INFECTED ANIMALS FROM VACCINATED ANIMALS

摘要

The present invention provides kits and devices for diagnosis of brucellosis and differentiation of infected animals from vaccinated animals. The invention represents an advancement in the field of immunoassay devices and kits. The proteins and peptide-based devices and kits disclosed in this invention have DIVA capabilities and can be used for differentiating Brucellosis-infected cattle from Brucella abortus S19-vaccinated cattle. Further, the devices and kits can be used for cost-effective, effective and efficient diagnosis of Brucellosis in a number of subjects with high sensitivity and specificity.