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COMPOSITION FOR DIAGNOSIS OR PROGNOSIS PREDICTION OF GLIOMA, AND METHOD FOR PROVIDING INFORMATION RELATED THERETO
COMPOSITION FOR DIAGNOSIS OR PROGNOSIS PREDICTION OF GLIOMA, AND METHOD FOR PROVIDING INFORMATION RELATED THERETO
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机译:诊断胶质瘤或预测胶质瘤的组合物,以及提供胶质瘤相关信息的方法
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摘要
The present invention relates to: a composition, a biomarker panel and a kit for the diagnosis or prognosis prediction of a glioma, all of which contain a drug for detecting a variation in a target gene; a method for providing information related to the diagnosis or prognosis prediction of a glioma; a biomarker panel for personalized medicine for a glioma; and a method for providing information for personalized treatment. According to one aspect, when a gene or protein variation is detected in one or more target genes selected from the group consisting of SAMD11, KLHL21, FAM167B, HPCAL4, GPBP1L1, LPHN2, GPR88, ZNF599, C19ORF33, B9D2, BCAM, CABP5, SIGLEC11, ERVV-2, ZNF865, MZF1, MRTO4, LRIG2, BSND, and SLC30A2, the diagnosis accuracy for a glioma diagnosis is high and the sensitivity is also high, and thus a glioma can be effectively diagnosed. Therefore, a drug for detecting a genetic variation in the target genes can be effectively used in a composition for the diagnosis or prognosis prediction of a glioma, a kit, a method for providing information, and a method for providing information for personalized treatment.
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