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GENETICALLY ENCODED TYROSINE SULFATION OF PROTEINS IN EUKARYOTES
GENETICALLY ENCODED TYROSINE SULFATION OF PROTEINS IN EUKARYOTES
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机译:真核生物中蛋白质的基因编码酪氨酸硫化
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摘要
An engineered tyrosyl-tRNA synthetase/tRNA pair that co-translationally incorporates O-sulfotyrosine in response to UAG codons in E. coli and mammalian cells is described herein. This platform enables recombinant expression of eukaryotic proteins homogeneously sulfated at chosen sites.
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