MEANS AND METHODS OF TREATING BURKITT LYMPHOMA OR LEUKEMIA

摘要

The present invention relates to a method of treating Burkitt lymphoma or leukemia in a patient, the method comprising administering to said patient a composition comprising a CD19xCD3 bispecific antibody in at least one treatment cycle, wherein the treatment cycle comprises administering a first dose of 15 μg/m²/d of the CD19xCD3 bispecific antibody for a first period of time of 4 days, and administering after the first dose a second dose of 60 μg/m²/d of the CD19xCD3 bispecific antibody for a second period of time, wherein the second period of time exceeds the first period of time.