首页> 外国专利> ELUCIDATING A PROTEOMIC SIGNATURE FOR THE DETECTION OF INTRACEREBRAL ANEURYSMS

ELUCIDATING A PROTEOMIC SIGNATURE FOR THE DETECTION OF INTRACEREBRAL ANEURYSMS

机译:消除蛋白蛋白信号以检测脑室内动脉瘤

摘要

Systems and methods for detecting an intracranial aneurysm in a test subject are provided. Liquid biological samples are obtained from the test subject, each liquid biological sample comprising a plurality of protein analytes. Liquid biological samples are analyzed using an immunoassay, obtaining a test dataset comprising a plurality of abundance measures. Each abundance measure corresponds to a respective protein analyte in the plurality of protein analytes. The test dataset is inputted into a trained classifier, obtaining an indication from the trained classifier that the subject has an intracranial aneurysm, based at least in part on the plurality of abundance measures for the test subject in the test dataset.
机译:提供了用于在测试对象中检测颅内动脉瘤的系统和方法。从测试对象获得液体生物样品,每个液体生物样品包含多种蛋白质分析物。使用免疫测定法分析液体生物样品,以获得包括多种丰度量度的测试数据集。每个丰度量度对应于多种蛋白质分析物中的相应蛋白质分析物。将测试数据集输入训练有素的分类器中,至少部分地基于测试数据集中测试对象的多个丰度量度,从训练有素的分类器中获得受试者具有颅内动脉瘤的指示。

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