首页> 外国专利> Stable preparations of anti-TIGIT antibodies alone and in combination with programmed kill receptor 1 (PD-1) antibodies and methods of use thereof

Stable preparations of anti-TIGIT antibodies alone and in combination with programmed kill receptor 1 (PD-1) antibodies and methods of use thereof

机译:单独的抗TIGIT抗体的稳定制剂以及与程序性杀伤受体1(PD-1)抗体组合的稳定制剂及其使用方法

摘要

The present invention provides a stable preparation of an antibody against T cell immunoreceptors (TIGIT) having Ig and ITIM domains, optionally adding an anti-human programmed kill receptor 1 (PD-1) antibody or antigen binding fragment thereof. It relates to a stable formulation containing. Also provided are methods of treating various cancers and chronic infections using the formulations of the present invention.
机译:本发明提供了具有Ig和ITIM结构域的针对T细胞免疫受体(TIGIT)的抗体的稳定制剂,任选地添加了抗人程序性杀伤受体1(PD-1)抗体或其抗原结合片段。它涉及一种稳定的制剂。还提供了使用本发明的制剂治疗各种癌症和慢性感染的方法。

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