25- D2 D3 ANTIBODIES TO 25-HYDROXYVITAMIN D2 AND D3 AND USES THEREOF

摘要

Vitamin D derivatives such as 25-hydroxyvitamin D2 and / or 25-hydroxyvitamin D3, or 25-hydroxyvitamin D analogs, such as vitamin D-C22 immunogenic molecules or compounds Provided herein are antigenic molecules that can be used to generate antibodies that are present. Also described are antibodies generated using such antigenic molecules, and related antigenic compounds. Also, a method for detecting vitamin D deficiency in a subject. A method for treating a subject believed to have a vitamin D deficiency, a method for monitoring the progress of a vitamin D deficiency in a subject, and treatment of a vitamin D deficiency in a subject in need of monitoring the treatment of a vitamin D deficiency Disclosed herein are methods for monitoring. Methods and reagents for the detection or quantification of 25-hydroxyvitamins D2 and D3, methods for stabilizing vitamin D analogs, and methods for separating 25-hydroxyvitamins D2 and D3 from vitamin D binding proteins in biological samples Also provided.