首页> 外国专利> 4'- 4'-phosphopantetheinyl transferase enzyme inhibitors derived from Mycobacterium tuberculosis and pharmaceutical composition for use in preventing or treating tuberculosis containing the same as an active ingredient

4'- 4'-phosphopantetheinyl transferase enzyme inhibitors derived from Mycobacterium tuberculosis and pharmaceutical composition for use in preventing or treating tuberculosis containing the same as an active ingredient

机译:源自结核分枝杆菌的4'- 4'-磷酸泛锡基转移酶抑制剂和用于预防或治疗含有其作为有效成分的结核病的药物组合物

摘要

The present invention relates to a 4'-phosphopantetheinyl transferase enzyme inhibitor derived from Mycobacterium tuberculosis and a pharmaceutical composition for preventing or treating tuberculosis containing the same as an active ingredient, according to the present invention. Compounds can significantly inhibit 4'-phosphopanthethenyl transferase enzyme to remove Mycobacterium tuberculosis through an immune response in the body, thereby having an effect that can be used for the prevention or treatment of tuberculosis.
机译:本发明涉及一种根据本发明的源自结核分枝杆菌的4′-磷酸泛锡基转移酶抑制剂和用于预防或治疗该结核病的药物组合物。化合物可通过体内的免疫反应显着抑制4'-磷酸泛蒽基转移酶去除结核分枝杆菌,从而具有可用于预防或治疗结核病的作用。

著录项

  • 公开/公告号KR102051449B1

    专利类型

  • 公开/公告日2019-12-03

    原文格式PDF

  • 申请/专利权人 서울대학교산학협력단;

    申请/专利号KR20170014330

  • 发明设计人 이봉진;이규연;김동균;이상재;

    申请日2017-02-01

  • 分类号C07D277/66;A23L33/10;A61K31/4196;A61K31/428;C07D263/57;C07D498/04;

  • 国家 KR

  • 入库时间 2022-08-21 11:08:22

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