首页> 外国专利> Cell for target position tracking using bio-orthogonal reaction kit for lesion diagnosis comprising the same and method for tracking target position in vivo using the same

Cell for target position tracking using bio-orthogonal reaction kit for lesion diagnosis comprising the same and method for tracking target position in vivo using the same

机译:使用用于诊断病变的生物正交反应试剂盒进行目标位置跟踪的细胞以及使用该试剂盒在体内跟踪目标位置的方法

摘要

The present invention relates to a cell for tracking a target location using a bio-orthogonal reaction, a kit for diagnosing a lesion comprising the same, and a method for tracking a target location in vivo using the same, more specifically, positron emission tomography (PET) The present invention relates to a cell tracking imaging method, wherein a cell for tracking a target location loaded with porous nanoparticles connected with a bio-orthogonal functional group according to the present invention can not only target the in vivo target location at a high target rate compared to the prior art. In addition, since the porous nanoparticles are loaded in the target tracking cell for a long time, using a labeling compound, there is a useful effect of repeatedly obtaining a high reliability PET image for a long time.
机译:本发明涉及一种使用生物正交反应追踪靶标位置的细胞,一种用于诊断病变的试剂盒以及使用该试剂盒在体内追踪靶标位置的方法,更具体地,涉及一种正电子发射断层扫描( PET)本发明涉及细胞跟踪成像方法,其中用于跟踪装载有根据本发明的连接有生物正交官能团的多孔纳米颗粒的靶位置的细胞不仅可以将体内靶位置靶向高目标率与现有技术相比。另外,由于多孔纳米颗粒使用标记化合物长时间装载在目标跟踪单元中,因此具有长时间重复获得高可靠性PET图像的有用效果。

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