首页> 外国专利> COMPOSITION FOR PREVENTING OR TREATING PEYRONIES DISEASE COMPRISING VITRIN INHIBITOR

COMPOSITION FOR PREVENTING OR TREATING PEYRONIES DISEASE COMPRISING VITRIN INHIBITOR

机译:包含维特林抑制剂的预防或治疗V病的组合物

摘要

The present invention relates to a composition for preventing or treating Peyronies disease comprising an inhibitor of vitrin as an active component. The inhibitor of vitrin according to the present invention reduces fibrotic lesions of penile membranes, inhibits the expression of vitrine in fibroblasts to inhibit the contraction of extracellular matrix and adhesion of cells and extracellular matrix by TGF-. The inhibitor of vitrin has an excellent effect of inhibiting tissue fibrosis by reducing the synthesis of extracellular matrix, thereby being able to be usefully used for preventing or treating Peyronies disease.;COPYRIGHT KIPO 2020
机译:本发明涉及用于预防或治疗Peyronies疾病的组合物,其包含玻璃蛋白抑制剂作为活性成分。本发明的玻璃体蛋白抑制剂减少了阴茎膜的纤维化损伤,抑制了成纤维细胞中玻璃体蛋白的表达,从而抑制了TGF-β对细胞外基质的收缩以及细胞和细胞外基质的粘附。 vitrin抑制剂通过减少细胞外基质的合成,具有抑制组织纤维化的优异效果,因此可有效地用于预防或治疗Peyronies疾病。; COPYRIGHT KIPO 2020

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