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Bacterial cell membrane-adherent bioactive glass nanoparticles

机译:细菌细胞膜粘附生物活性玻璃纳米颗粒

摘要

The present invention relates to bacterial cell membrane-adherent bioactive glass nanoparticles comprising SiO_2, CaO, and AgO, having a particle size of 1 to 100 nm, and having mesoporous pores. Bacterial cell membrane-adherent bioactive glass nanoparticles simultaneously deliver living body cell-stimulating ions and antimicrobial drugs to stimulate stem cells to differentiate cells of infected hard tissues and at the same time to have an effect of protecting hard tissues from bacteria. In addition, by controlling a size of glass nanoparticles to a nano size, glass nanoparticles are attached to a cell membrane of bacteria, thereby being able to efficiently transfer ions and antimicrobial drugs into bacteria.
机译:本发明涉及粘附有细菌细胞膜的生物活性玻璃纳米颗粒,其包含SiO 2,CaO和AgO,其粒径为1至100nm并且具有中孔。附着有细菌细胞膜的生物活性玻璃纳米颗粒可同时递送刺激活细胞的离子和抗菌药物,以刺激干细胞分化受感染的硬组织的细胞,同时具有保护硬组织免受细菌侵害的作用。另外,通过将玻璃纳米颗粒的尺寸控制为纳米尺寸,玻璃纳米颗粒附着在细菌的细胞膜上,从而能够有效地将离子和抗菌药物转移到细菌中。

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