Serotonin reuptake inhibitor-based antidepressant responsiveness modulating peptides and uses thereof

摘要

Provided are: a peptide for regulating reactivity to a serotonin reuptake inhibitor-based antidepressant; a vector comprising the peptide; and a pharmaceutical composition for preventing or treating depression, comprising the peptide. The peptide is directly involved in the formation of a p11/AnxA2/SMARCA3 complex, thereby effectively regulating the reactivity to the serotonin reuptake inhibitor-based antidepressant.