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DRUG AND GENE CO-DELIVERY SYSTEM BASED ON CELL PERMEABLE ADHESIVE PROTEIN NANOPARTICLES

机译:基于细胞渗透性胶体纳米颗粒的药物与基因共递送系统

摘要

The present invention relates to a mucoadhesive protein-based cell permeable adhesive protein and a drug and gene co-delivery system through nanoparticles using the same. When the cell permeable adhesive protein of the present invention is used, the intracellular permeability of the mussel adhesive protein can be increased to increase intracellular delivery efficiency. The nanoparticles of the present invention can simultaneously load drugs and genes, as well as has increased intracellular permeability, thereby efficiently delivering desired drugs or genes into cells. Therefore, desired effects can be maximized.;COPYRIGHT KIPO 2020
机译:本发明涉及基于粘膜粘附蛋白的细胞可渗透粘附蛋白以及通过使用其的纳米颗粒的药物和基因共递送系统。当使用本发明的细胞可渗透粘附蛋白时,贻贝粘附蛋白的细胞内渗透性可增加以增加细胞内递送效率。本发明的纳米颗粒可以同时加载药物和基因,并具有增加的细胞内通透性,从而有效地将所需的药物或基因递送到细胞中。因此,可以最大程度地获得预期的效果。; COPYRIGHT KIPO 2020

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