Method for simple fluid engineering of nanopore

摘要

Aspects disclosed herein are methods of mass manufacturing an array of biological sensing devices on a substrate, each of the biological sensing devices having a vertical or horizontal membrane, the membrane having one or more solid state nanopores through it. , And methods for simple hydrodynamic treatment of each nanopore. In one aspect, a method for forming nanopores by applying a voltage from a positive electrode to a negative electrode through a freestanding membrane is disclosed. In other aspects, a method for forming a plurality of nanopores on a wafer is disclosed. In another aspect, a single side processing method for forming a nanopore device is disclosed for providing a device having baths on both sides of a nanopore processable from a single side of a substrate. In another aspect, a method for fluidically processing a plurality of nanopore devices is disclosed.