VIII FVIII MULTISPECIFIC ANTIGEN-BINDING MOLECULES HAVING BLOOD COAGULATION FACTOR VIII FVIII COFACTOR FUNCTION-SUBSTITUTING ACTIVITY AND PHARMACEUTICAL FORMULATIONS CONTAINING SUCH A MOLECULE AS AN ACTIVE INGREDIENT

摘要

It has been successful to find bispecific antibodies that do not increase FIX activation inhibitory activity and also increase FVIII carrier function replacement activity.